West Brom, relegated from the Premier League last season, made 11 changes from the side that won at the weekend in the Championship and had five players -- including goalkeeper Alex Palmer -- making their debuts.
ManchesterCity manager Pep Guardiola has expressed doubts over whether Manchester United can challenge for the Premier League title but believes they have a realistic chance of finishing in the top four.
The Gunners' only league defeat of the campaign was in September away to one of England's traditional top-six clubs, Manchester United, drawing criticism that their strong start to the season was based on wins against lesser opposition.
;You will have setbacks. We beat Arsenal, we beat Liverpool. On Sunday, we had a bad day at the office. City were better, we have to accept that. But we can't accept our unacceptable performance. So thank you for the lesson, Pep and City. We have to understand, we have to do things much better.'
Arsenal had more than twice as many chances but failed to take any as the visitors defended gamely.
Jose Mourinho's wretched week ended on a high note as Manchester United's big guns Zlatan Ibrahimovic and Paul Pogba finally began firing, both finding the target in a 3-1 win at dismal Swansea City on Sunday. Mourinho watched from the stands at the Liberty Stadium following his touchline ban imposed by the Football Association on Wednesday and was buoyed to see Ibrahimovic score twice -- his first league goals in eight weeks -- and Pogba net a superb volley. United, vastly improved after their midweek Europa League defeat at Fenerbahce, went ahead with a 15th minute strike from Pogba worthy of his 89 million pounds price tag before Ibrahimovic ended his goal drought with a sharp first-half double in the space of 12 minutes.
Brazil, who are fifth in the CONMEBOL table with 18 points from 12 games, host Colombia on March 21 and visit Argentina five days later in a match that could see Neymar come up against former Barcelona and Paris St Germain teammate Lionel Messi.
Arsenal manager Arsene Wenger was facing the biggest crisis of his career after Sunday's 8-2 mauling by Manchester United but the Frenchman vowed not to panic on the field or in the transfer market with fans questioning his future for the first time.
Arsenal thrashed Middlesbrough 7-0, while Manchester United lost 3-1 at Manchester City in the Premier League.
Manchester United have knocked champions Arsenal out of the title race with Tuesday's emphatic 4-2 victory at Highbury, according to both teams' managers.
Manchester United and Manchester City left their tortured opponents and the Premier League in no doubt they are the teams to beat this season after hugely confident demolitions of Arsenal and Tottenham Hotspur on Sunday.
Arsenal shoved Chelsea off the top of the table but Leicester City's Jamie Vardy, with a dazzling hat-trick, was the man of the moment on Saturday as the struggling Premier League champions blew aside Manchester City 4-2.
Arsenal have the chance to return to the top when they visit Bolton Wanderers on Saturday.
Holders Manchester City were eliminated from the League Cup by West Ham United after a penalty shootout at London Stadium on Wednesday, ending Pep Guardiola's team's four-year domination of the competition.
Arsenal manager hailed Thierry Henry as "world class" after the prolific striker netted his 100th premier league goal against Southampton on Tuesday.
Images from the English Premier League matches played on Tuesday.
News of all that's transpired on and off the football field
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game in charge of Liverpool was solid rather than spectacular with his new side drawing 0-0 at Tottenham Hotspur in the Premier League on Saturday.
The sporting world, from football giants Manchester United to glamorous tennis star Maria Sharapova, has united to help raise money for victims of Asia's tsunami disaster.
Arsenal remain top on 37 points, one ahead of Manchester United who beat bottom club Derby County 4-1 on Saturday while Chelsea are two points further back after beating Sunderland 2-0.
Arsenal's 2-1 Champions League win at Montpellier on Tuesday was another sign the club is building real momentum this season, and it could not have come at a better time with Premier League champions Manchester City up next.
An intoxicating day of Premier League action on Saturday ended with leaders Manchester United beaten for the first time this season, title rivals Arsenal blowing a 4-0 lead and a record 41 goals across eight fixtures.
Something will have to give when in-form Liverpool and bitter rivals Manchester United clash in one of the Premier League's showcase fixtures at Anfield on Sunday.
Images from the English Premier League matches played on Wednesday night.
Manchester United manager Alex Ferguson predicted on Friday the Premier League title will be won by either his team or their fierce rivals Manchester City.
Robert Pires and Jermaine Pennant fired hat-tricks in a 6-1 win, a dress rehearsal for next week's FA Cup final.
Images from the EPL matches played on Sunday.
Arsenal will begin their quest to become the first club since 1886 to win the English FA Cup three years in succession.
Arsenal bounced back from their shock defeat by Birmingham City in the League Cup final when Denmark striker Nicklas Bendtner scored a hat-trick in a 5-0 demolition of Leyton Orient in the FA Cup on Wednesday.
'It's not easy to handle a team at a big, big club... always demanding to win competitions and every manager needs time. I have the feeling United started to play the way he wants'
The team was forced into self-isolation after manager Mikel Arteta tested positive for Coronavirus earlier this month.